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Rash Statements
For: Ask the Experts, October 2002

The rash caused by poison ivy is an immune-system reaction to an oil called urushiol (uh-ROO-she-all) that occurs in the sap of the plant genus Toxicodendron. Poison ivy, oak, and sumac all belong to this genus (cashews and mangos are close relatives).

How can you avoid an outbreak? Stay away from the plants, if you can. Wear protective clothing, including gloves, when out in the woods or working in the yard. Learn to recognize the leaves and berries of the toxicodendrons common to your area.

The FDA recently approved a nonprescription liquid called Ivy Block ($12 for 4 ounces) that has been shown to prevent or minimize the rash. Its active ingredient is bentoquatum—a clay filler that blocks absorption of urushiol. It may be useful for those who work and play outdoors and can't avoid the plants. (It has not been tested on children under 6.) You spread it on your skin before exposure; it leaves a visible coating so you can tell where it is.

Will eating a few leaves of the plant desensitize you? Not at all. And it may make you very sick.

Do pets get poison ivy? No, but they can carry urushiol on their fur and spread it to you. Bathe your pet, wearing gloves, if you think it has brushed against a toxicodendron.

Will scratching the rash (and breaking the blisters) cause it to spread? No. The water inside the blisters does not contain urushiol. But try not to scratch anyway, because scratching can lead to infection. If the rash seems to have spread to areas of your body that were protected by clothing, you may unknowingly have had urushiol on your hands or clothing and spread it. If you think you've been exposed, be careful when undressing.

How do you get rid of urushiol once it is on your skin or clothing? If you think you have been exposed, wash the area with soap and lots of water within 5 to 10 minutes, if possible. The longer you wait, the less effective washing becomes. If you're out in the woods, use water from a lake or stream, premoistened towelettes, rubbing alcohol, or even soda or beer from the picnic basket. Wear gloves to remove clothing and shoes. Wash clothes in strong detergent, and wipe off shoes. Urushiol is very durable. If you don't wash it off shoes, garden tools, and other items, it will still be there many months hence and can cause a reaction.

Can the rash be transmitted from person to person? No. By the time the rash appears, the urushiol is gone. In theory, if you have urushiol on your skin—that is, after exposure to the plant but before the rash appears, you might transmit the oil by touching someone. But this is not a common means of transmission.

Is anyone immune to poison ivy? It's thought that up to 70% of us are sensitive. But you may not start reacting until you've been exposed a few times. Never count on being immune.

Are there areas where the plants don't grow? Toxicodendrons are common nearly everywhere from Mexico to Canada. The only states that have none are Nevada, Hawaii, and Alaska. Some states have no poison ivy but do have poison oak.

Is it just the leaves that cause the problem? All parts of the plant can be toxic, even if dead. If you are trying to rid your yard of it, you can kill it with a herbicide, but you'll still need to wear heavy protective gloves and clothing when removing the "corpses."

Is it a good idea to burn the plants? No, that can release urushiol into the air. This is a danger in forest fires, especially for firefighters.

How can you relieve the itch? Cool compresses, cool baths, calamine lotion or cream, baking soda baths or compresses, or colloidal oatmeal baths all have their advocates. Nonprescription cortisone creams can also help. The rash usually lasts less than three weeks and itches less as time goes on. But if it is widespread and very painful, see a doctor, who may prescribe a corticoid product.

UC Berkeley Wellness Letter, August 1997

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